Kalpana Chawla

Kalpana Chawla was an aerospace engineer and the first Indian American woman in space on NASA's 1997 Columbia space shuttle mission (STS-87) as a robotic arm operator. Chawla was a mission specialist on the Columbia shuttle's STS-107 mission in 2003 and died when the shuttle disintegrated upon re-entry after its 16-day flight.

Source: https://www.space.com/17056-kalpana-chawla-biography.html